We are in constant pursuit of breakthroughs that transform patients' lives. We create innovations daily to make the world a better place. This was Charles Pfizer's original vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies deliver better results, are more creative, recruit and maintain the best professionals, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and shows our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and reflects the value we strive to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We embody our purpose by finding the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.