We are in constant pursuit of breakthroughs that improve patients' lives. We create innovations daily to make the world a more healthy place. It was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more inventive, recruit and maintain the best people, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and reflects our passion for growing our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and embodies the value we aim to bring to patients and society. Our purpose makes certain that patients continue to be at the centre of all we do. We embody our purpose by finding the best science in the world, working with others in the healthcare system to improve access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.