We are in constant pursuit of breakthroughs that change patients' lives. We innovate every day to make the world a better place. It was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more inventive, attract and retain the best professionals, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and reflects our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and represents the value we aim to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We fulfill our purpose by finding the best science in the world, working with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.