We are in constant pursuit of breakthroughs that change patients' lives. We innovate each day to make the world a better place. It was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more innovative, attract and retain the best talent, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that improve patients' lives—fuels everything we do and demonstrates our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and embodies the value we work to bring to patients and society. Our purpose ensures that patients stay at the centre of all we do. We embody our purpose by sourcing the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, using digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.