We are in relentless pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a healthier place. This was Charles Pfizer's initial vision, and it holds true today. Studies show what we instinctively know: that purpose-driven companies achieve more, are more creative, draw and keep the best professionals, and know how to harness the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and reflects our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and reflects the value we work to bring to patients and society. Our purpose makes certain that patients continue to be at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to increase access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.