We are in constant pursuit of breakthroughs that change patients' lives. We innovate daily to make the world a healthier place. It was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more innovative, recruit and maintain the best talent, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and shows our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and reflects the value we strive to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We fulfill our purpose by seeking the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to campaign for pro-innovation/pro-patient policies. Every choice we make, and every move we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.