We're in constant pursuit of breakthroughs that improve patients' lives. We create innovations daily to make the world a better place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more creative, draw and keep the best professionals, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and shows our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and reflects the value we work to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We live our purpose by finding the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to campaign for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.