We are in constant pursuit of breakthroughs that transform patients' lives. We innovate daily to make the world a more healthy place. It was Charles Pfizer's initial vision, and it remains true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, recruit and maintain the best professionals, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and demonstrates our passion for growing our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and reflects the value we aim to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We embody our purpose by sourcing the best science in the world, working with others in the healthcare system to enhance access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every decision we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.