We are in tireless pursuit of breakthroughs that change patients' lives. We create innovations every day to make the world a healthier place. This was Charles Pfizer's original vision, and it holds true today. Research confirms what intuition tells us: that purpose-driven companies deliver better results, are more inventive, attract and retain the best people, and know how to harness the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and shows our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and reflects the value we strive to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We fulfill our purpose by seeking the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, using digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.