We are in tireless pursuit of breakthroughs that change patients' lives. We drive innovation every day to make the world a better place. It was Charles Pfizer's original vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, draw and keep the best talent, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and shows our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and reflects the value we aim to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.