We are in constant pursuit of breakthroughs that change patients' lives. We innovate daily to make the world a better place. This was Charles Pfizer's original vision, and it remains true today. Research confirms what we instinctively know: that purpose-driven companies achieve more, are more inventive, draw and keep the best talent, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and reflects our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and embodies the value we strive to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to increase access to our medicines, using digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.