We are in tireless pursuit of breakthroughs that transform patients' lives. We create innovations each day to make the world a better place. This was Charles Pfizer's initial vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, recruit and maintain the best talent, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and demonstrates our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has meaning and represents the value we aim to bring to patients and society. Our purpose makes certain that patients stay at the centre of all we do. We embody our purpose by seeking the best science in the world, working with others in the healthcare system to improve access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.