We are in relentless pursuit of breakthroughs that improve patients' lives. We create innovations each day to make the world a better place. It was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, draw and keep the best talent, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and represents the value we work to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We embody our purpose by finding the best science in the world, working with others in the healthcare system to increase access to our medicines, utilizing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.