We are in relentless pursuit of breakthroughs that transform patients' lives. We create innovations daily to make the world a healthier place. It was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more creative, draw and keep the best professionals, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that improve patients' lives—drives everything we do and shows our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and represents the value we work to bring to patients and society. Our purpose ensures that patients stay at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can prosper.