We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation each day to make the world a more healthy place. This was Charles Pfizer's founding vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more creative, draw and keep the best talent, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and shows our passion for growing our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has meaning and embodies the value we aim to bring to patients and society. Our purpose makes certain that patients continue to be at the centre of all we do. We live our purpose by seeking the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can flourish.