We are in constant pursuit of breakthroughs that transform patients' lives. We create innovations daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it holds true today. Research confirms what intuition tells us: that purpose-driven companies deliver better results, are more creative, draw and keep the best professionals, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and reflects the value we strive to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We live our purpose by sourcing the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can prosper.